Retatrutide Dose Calculator
Enter the vial, the reconstitution water and this week's dose. You get the exact mark on the syringe, the vial's concentration and how many injections it still holds.
Water doesn't change the dose — it changes how many units the dose takes up.
U-100 and U-50 share the same scale — 100 units per mL. The U-50 just has half the barrel (0.5 mL), so it stops at 50. The U-40 marks 40 units per mL, which is a different scale. Check what's printed on yours.
Fill in the vial, the water and the dose to see the result.
Personal journal. Not medical advice.
How the retatrutide calculation works
Large vials and a wide dose range make the dilution matter more here than with other compounds. The steps below use a 10 mg vial in 2 mL.
Concentration
Milligrams in the vial ÷ mL of water = how many mg sit in each mL.
vial ÷ water = concentration10 mg ÷ 2 mL = 5 mg/mLVolume per dose
Dose ÷ concentration = how many mL you need to draw.
dose ÷ concentration = mL1 mg ÷ 5 = 0.2 mLUnits on the syringe
mL × 100 on a U-100 or U-50 syringe (or × 40 on a U-40) = the mark to stop at.
mL × 100 = units0.2 mL × 100 = 20 unitsThe whole thing in one formula
units = dose ÷ (vial ÷ water) × 100Vial in mg, water in mL, dose in mg. The 100 covers U-100 and U-50; swap it for 40 if your syringe is a U-40.
A 10 mg vial with 2 mL of water gives 5 mg/mL. A 1 mg dose takes up 0.2 mL — that's 20 units on a U-100 syringe.
The conversions people look up
How many units is 1 mg of retatrutide?
20 units on a U-100, with a 10 mg vial reconstituted in 2 mL.
And 2 mg and 4 mg?
40 and 80 units in the same vial — both still fit in one injection.
And 8 mg?
160 units at that dilution, which doesn't fit. With 1 mL of water (10 mg/mL), the same dose lands on 80 units.
What's the concentration of a 10 mg vial in 2 mL?
5 mg/mL. With 3 mL it would be 3.33 mg/mL, and 1 mg would take up 30 units.
Units by dose and dilution
A 10 mg vial on a U-100 syringe. Columns are the water you used to reconstitute.
| Dose | 1 mL | 2 mL | 3 mL |
|---|---|---|---|
| 1 mg | 10 | 20 | 30 |
| 2 mg | 20 | 40 | 60 |
| 4 mg | 40 | 80 | 120 |
| 8 mg | 80 | 160 | 240 |
| 12 mg | 120 | 240 | 360 |
Retatrutide in context
Retatrutide is a triple agonist: it acts on GLP-1, GIP and glucagon receptors at once. It's an investigational compound — no regulatory approval, still in clinical study. That means there's no package insert, no official titration schedule, and no guaranteed quality control on anything circulating outside the trials.
In published studies the tested doses were weekly and covered a wide range, from about 1 mg up to 12 mg, always with gradual escalation over months. Starting high isn't part of any research protocol — the steps exist precisely so tolerance can build.
Because it's a moving target, the math changes often: vials come in different sizes, protocols differ from source to source, and the dilution is rarely the same twice. Recording what you actually did each time — vial, water, dose, date — is what turns this into something you can review later.
Do this math once. Once.
In PepPro you enter the vial and the water a single time. From then on the app works out every injection on its own, shows the units on a visual syringe, reminds you at the right moment and keeps the whole history.
- Your reconstitution stays saved per vial
- Exact units on a visual syringe before you inject
- Reminders, titration and injection-site rotation
- Full history of doses, weight and how you feel
Exact units on a visual syringe before you inject
Good question. We've got answers.
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Yes, that's the normal use. A reconstituted 10 mg vial gives ten 1 mg injections or five at 2 mg, drawn over the following weeks. What needs care is wiping the stopper before every puncture and keeping storage right between injections.
It's the same procedure as any lyophilized peptide: vial at room temperature, stopper wiped with alcohol, bacteriostatic water running down the inner wall, gentle swirling until dissolved, no shaking. Then refrigerate and keep it away from light.
1 mL to 3 mL covers the dose range well. With 2 mL, 1 mg sits at 20 units and 4 mg at 80 — still inside a U-100 syringe. If you're already on higher doses, less water keeps everything in a single injection.
No. As far as is publicly known it remains an investigational compound in clinical trials, without approval from agencies such as the FDA, EMA or Anvisa. Any use outside a study is at the user's own risk, and this calculator is not an endorsement of it.
Ten injections at 1 mg, five at 2 mg or two at 4 mg — the amount of water doesn't change that number, only how big the mark on the syringe is. The calculator shows doses per vial alongside the result.
Yes — that's exactly what PepPro is for. Enter the vial and the reconstitution once and the app takes over: it works out every injection, shows the units on a visual syringe, reminds you when it's time and keeps the history of doses, weight and how you feel.
No. PepPro is a personal journal and this calculator is an educational tool. Nothing here replaces a qualified healthcare professional — they're the one who decides whether, how much and how you should use any compound.
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Personal journal. Not medical advice.
Disclaimer
This calculator is for informational and educational purposes only and is not medical advice. Always confirm dosing with a qualified healthcare professional and double-check your own measurements before administering anything.